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医疗设备产业及市场展望研究报告2012-2022年
Medical Devices Industry and Market Prospects 2012-2022

医疗设备产业及市场展望研究报告2012-2022年
【报告编号】:No.2715
【发布时间】:2012-07
【关 键 字】:医疗设备   Medical Devices   
【报告页数】:144页
【报告价格】:电子版:2739美元
【交付方式】:Email发送或EMS快递
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Abstract

In 2011, the medical device market worldwide was worth $266.0bn, with high single-digit growth from the year before. Despite being a vast and mature market, there are number of sectors likely to experience fast growth during the next 10 years. Much of this growth is linked to the prevalence of a number of diseases worldwide, as well as an aging population. The rise in neurological disorders will drive both the diagnostics market and the neurological device market. Changes in wealth and lifestyle globally, particularly in the emerging markets, will lead to a rise in obesity and coronary diseases.
As a result, the medical device market is one of the largest sectors in the global healthcare industry. All sectors of the market have been expanding, but which will grow fastest in years to come? What trends in global disease will shape the industry in the future? How will the principal national markets perform from 2012 to 2022? What will happen to the current leading products? What growth can be expected by emerging markets such as China and India? How will recent Health Care Reform in the US affect the market over the next 10 years? This report will answer those and other crucial questions about this large, and growing, market.
Medical Devices Industry and Market Prospects 2012-2022 provides an in-depth analysis of the medical device market, paying particular attention to the cardiology and neurological device markets. The report uses a wealth of research tools - including market forecasting, qualitative analyses, probing interviews with industry experts, literature searches and use of commercial databases. The report is packed with original data in tables, charts and other formats.
Visiongain predicts that the global medical device market will continue to grow steadily from 2012-2022, driven by increasing prevalence of neurological and coronary disorders, and an aging global population. In some countries markets will expand rapidly in the coming years, whilst in others the market will show only moderate growth. By purchasing this report, you will find out by how much the medical device market will grow and which countries will achieve the most rapid market growth. This report provides our sales forecasts, market share analyses, discussions of technological developments and analyses of commercial drivers and restraints, including SWOT analysis and Porter's five force analysis.

Why you should buy Medical Devices Industry and Market Prospects 2012-2022

In this report, you will receive the following benefits in particular:
  • You will receive a comprehensive analysis of the prospects for medical device industry as a whole from 2012 to 2022, including predicted market sizes, growth rates and other metrics for leading sectors
  • You will receive a comprehensive analysis of the leading companies in the medical device industry in 2011
  • You will receive an overall forecast for the cardiology device market from 2012 to 2022, as well as that for the drug eluting coronary stent market, with comprehensive discussions and other supporting information
  • You will receive an overall forecast for the neurological device market from 2012 to 2022, as well as that for neuromodulation device classes (deep brain stimulation, spinal cord stimulation and vagus nerve stimulation), with comprehensive discussions and other supporting information
  • You will discover revenue forecasts to 2022 for leading national markets (US, Japan, Europe, China and India), seeing growth trends
  • You will receive a comprehensive analysis of the leading companies in the medical device industry in 2011
  • You will find out where the market is heading - both technologically and commercially - from 2012 onwards
  • You will discover the drivers, restraints, competition and opportunities influencing the medical device market, with particular attention paid to drug eluting coronary stents and neuromodulation devices
  • You will identify where new opportunities lie in these sectors, with new therapeutic areas and commercial opportunities discussed
  • You will view opinions from our industry survey, receiving full interview transcripts.
Medical Devices Industry and Market Prospects 2012-2022 shows you opportunities, challenges and revenue forecasts. That mix of quantitative and qualitative analysis sets our report apart. We tackle crucial questions in the medical device industry and market, aiming to save you time and effort.

You can order this report today

Order our report now to gain industry and market analysis for medical device market.
Our report is for everybody interested in market analysis, product development, sales and marketing for devices. You will find predictions and answers. Don't miss out - please order our report now.
Visiongain is a trading partner with the US Federal Government.

Table of Contents

1. Executive Summary

  • 1.1. Sector Highlights
  • 1.2. Overview of the Chapter Content
  • 1.3. Research and Analysis Methods
  • 1.4. Glossary of Terms Related to the Report

2. An Introduction to the Medical Device Industry

  • 2.1. Classification of Medical Devices
    • 2.1.1. The US Classification System
    • 2.1.2. The EU Classification System
  • 2.2. Regulation of Medical Devices
    • 2.2.1. The US Approval and Regulation System
    • 2.2.2. The EU Approval and Regulation System
  • 2.3. Coronary Artery Disease and Coronary Stents
    • 2.3.1. Bare Metal Stent
    • 2.3.2. Drug Eluting Stents (DES)
    • 2.3.3. Drugs Used in DES
      • 2.3.3.1. Sirolimus
      • 2.3.3.2. Everolimus
      • 2.3.3.3. Zotarolimus
      • 2.3.3.4. Paclitaxel
  • 2.4. Neuromodulation
    • 2.4.1. Chronic Pain and Spinal Cord Stimulation
    • 2.4.2. Parkinson's Disease and Deep Brain Stimulation
      • 2.4.2.1. Parkinson's Disease
      • 2.4.2.2. Deep Brain Stimulation
      • 2.4.2.3. Epilepsy and Vagus Nerve Stimulation

3. The Global Medical Device Market, 2011-2022

  • 3.1. Medical Devices: Market Overview
    • 3.1.1. Size of the Medical Device Market
    • 3.1.2. Medical Devices: Revenue Analysis by Company, 2011
      • 3.1.2.1. Johnson & Johnson
      • 3.1.2.2. GE Healthcare
      • 3.1.2.3. Siemens Healthcare
      • 3.1.2.4. Medtronic
      • 3.1.2.5. Baxter International
      • 3.1.2.6. Philips Healthcare
      • 3.1.2.7. Roche
      • 3.1.2.8. Abbott Laboratories
      • 3.1.2.9. Stryker Corporation
      • 3.1.2.10. Becton, Dickinson & Co.
      • 3.1.2.11. Samsung: A New Entry Into the Market
  • 3.2. World Medical Device Market Forecast, 2012-2016
  • 3.3. World Medical Device Market Forecast, 2016-2022
  • 3.4. Regional Medical Device Market Forecast, 2012-2022
    • 3.4.1. The Market in the US, Europe and Japan
      • 3.4.1.1. The US Market
      • 3.4.1.2. The European Markets
      • 3.4.1.3. The Japanese Market
    • 3.4.2. The Chinese and Indian Markets
      • 3.4.2.1. China
      • 3.4.2.2. India
  • 3.5. Changing Market Shares by Region, 2012-2022

4. Issues Affecting the Medical Device Market

  • 4.1. SWOT Analysis of the Medical Device Industry and Market, 2012-2022
  • 4.2. Strengths
    • 4.2.1. Large Number of Participating Companies
    • 4.2.2. Sustained Market Segmentation
    • 4.2.3. Strong Government Support Across Major International Markets
  • 4.3. Weaknesses
    • 4.3.1. The Market is Susceptible to Economic Pressures
    • 4.3.2. Much of the Market Has Reached Maturity
  • 4.4. Opportunities
    • 4.4.1. The Potential of Personalised Medicine
    • 4.4.2. An Aging Global Population
    • 4.4.3. Rapid Growth in Emerging Markets
    • 4.4.4. Increased Incidence and Prevalence of Many Diseases
    • 4.4.5. Regulatory Harmonisation Across Major International Markets
  • 4.5. Threats
    • 4.5.1. US Medical Device Excise Tax
    • 4.5.2. Changes to Reimbursement Globally
    • 4.5.3. Comparative Effectiveness Research as an Added Expense
  • 4.6. Porter's Five Force Analysis of the Medical Device Industry
    • 4.6.1. Rivalry Among Competitors (High)
    • 4.6.2. Threat of New Entrants (Low)
    • 4.6.3. Power of Suppliers (Low)
    • 4.6.4. Bargaining Power of Buyers (High)
    • 4.6.5. Threat of Substitutes (Low)

5. Cardiology and Thoracic Surgery Device Market, 2011-2022

  • 5.1. Cardiology and Thoracic Surgery Devices: Market Overview
    • 5.1.1. Cardiology and Thoracic Surgery Device Market in 2011
    • 5.1.2. Cardiology Device Market Forecast, 2012-2022
  • 5.2. The Drug Eluting Coronary Stent Market, Analysis & Forecast, 2011-2022
    • 5.2.1. The DES Market, 2011
    • 5.2.2. The DES Market Forecast, 2012-2016
    • 5.2.3. The DES Market Forecast, 2016-2022
  • 5.3. Leading Coronary Stent Product Analysis
    • 5.3.1. Taxus Paclitaxel-Eluting Stent (Boston Scientific)
      • 5.3.1.1. Disputes Over Paclitaxel-Eluting Stents
    • 5.3.2. Promus Everolimus-Eluting Stent (Boston Scientific)
    • 5.3.3. Xience Family of Everolimus-Eluting Stents (Abbott Vascular)
    • 5.3.4. Endeavor (Medtronic)
    • 5.3.5. Biomatrix (Biosensors International)
  • 5.4. Coronary Stent Pipeline
    • 5.4.1. Jactax (Boston Scientific)
    • 5.4.2. MiStent (MiCell Technologies)
    • 5.4.3. Synergy (Boston Scientific)
    • 5.4.4. BioFreedom (Biosensors International)
    • 5.4.5. Catania (CeloNova Biosciences)
    • 5.4.6. Genous Combo (OrbusNeich)
  • 5.5. Bioabsorbable Drug Eluting Stents
  • 5.6. SWOT Analysis of the DES Market, 2012-2022
    • 5.6.1. Strengths
      • 5.6.1.1. DES are More Effective than BMS
      • 5.6.1.2. Continous Innovation
      • 5.6.1.3. Continously-Evolving Market
    • 5.6.2. Weaknesses
      • 5.6.2.1. Stent Thrombosis
      • 5.6.2.2. The Success of DES Compared with Other Treatments
    • 5.6.3. Opportunities
      • 5.6.3.1. Increase in Coronary Artery Disease
      • 5.6.3.2. Moving Away From Dual Antiplatelet Therapy
    • 5.6.4. Threats
      • 5.6.4.1. Small Number of Companies Operating in the US and Japan
      • 5.6.4.2. The Drug May Become More Important than the Stent
      • 5.6.4.3. The DES Market is Still Emerging

6. Neurological Device Market, 2011-2022

  • 6.1. Neurological Devices: Market Overview
  • 6.2. Neurological Device Market Forecast, 2011-2022
  • 6.3. Neurostimulation Market Analysis and Forecast, 2012-2022
    • 6.3.1. Neuromodulation Market Forecast, 2012-2022
    • 6.3.2. SCS Market Forecast, 2012-2016
    • 6.3.3. SCS Market Forecast, 2016-2022
    • 6.3.4. DBS Market Forecast, 2012-2016
    • 6.3.5. DBS Market Forecast, 2016-2022
    • 6.3.6. VNS Market Forecast, 2012-2016
    • 6.3.7. VNS Market Forecast, 2016-2022
    • 6.3.8. Other Neuromodulation Devices Forecast, 2012-2022
  • 6.4. Changing Market Shares of the Leading Segments
  • 6.5. Neuromodulation Device Pipeline
    • 6.5.1. CVRx
    • 6.5.2. Apnex Medical
    • 6.5.3. ImThera Medical
    • 6.5.4. NeuroPace
    • 6.5.5. Intelect Medical (acquired by Boston Scientific Corporation)
    • 6.5.6. Devices for Treating Obesity
      • 6.5.6.1. EnteroMedics
      • 6.5.6.2. IntraPace
      • 6.5.6.3. MetaCure
  • 6.6. SWOT Analysis of the Neuromodulation Device Industry
    • 6.6.1. Strengths
      • 6.6.1.1. A Safer Alternative Treatment
      • 6.6.1.2. Neuromodulation as a Cost-Effective Treatment Option
      • 6.6.1.3. Neuromodulation Often Means Less Medication
    • 6.6.2. Weaknesses
      • 6.6.2.1. Neuromodulation Mechanisms are Not Well Understood
      • 6.6.2.2. A Small Number of Large Companies Dominate the Market
      • 6.6.2.3. FDA Approvals
      • 6.6.2.4. Many Devices Are Failing in Clinical Trials
    • 6.6.3. Opportunities
      • 6.6.3.1. Neuromodulation Market Set for Rapid Growth: Expanding Disease Indications
      • 6.6.3.2. Increasing Prevalence of Neurological Diseases
      • 6.6.3.3. Expansion into Emerging Markets
      • 6.6.3.4. The Potential of Personalised Medicine
    • 6.6.4. Threats
      • 6.6.4.1. Parkinson's Disease May Soon be Treated with Stem Cells
      • 6.6.4.2. SCS Faces Competition from Other Treatment Options
      • 6.6.4.3. Increasing Regulatory and Pricing Scrutiny in Emerging Markets

7. Expert Opinion

  • 7.1. Interview with Dr. Mateusz Zelewski, General Manager, MetaCure
    • 7.1.1. The Gastric Stimulation Market
    • 7.1.2. MetaCure's DIAMOND System
    • 7.1.3. The Importance of the Emerging Markets
    • 7.1.4. Public Perception of Gastric Stimulation
    • 7.1.5. Prospects for the Gastric Stimulation Market
  • 7.2. Interview with Michael Berman, Founder, Berman Medical
    • 7.2.1. The Neuromodulation Market
    • 7.2.2. Challenges Facing the Neuromodulation Market
    • 7.2.3. Prospects for the Neuromodulation Market
  • 7.3. Spokeperson from CVRx (Views Provided Anonymously)
    • 7.3.1. Barostim Neo: New Implantable Device for Hypertension
    • 7.3.2. On the Development of Barostim Neo
    • 7.3.3. Competition for Barostim Neo
    • 7.3.4. On the Unmet Needs in the Market

8. Conclusions

  • 8.1. The Medical Device Industry, 2012-2022
    • 8.1.1. Growth Will Be Driven by Emerging Markets
    • 8.1.2. Personalised Medicine Offers Opportunities to the Industry
  • 8.2. The Coronary Stent Market, 2012-2022
    • 8.2.1. Innovation Will Drive Growth in the DES Market
  • 8.3. The Neuromodulation Market, 2012-2022
    • 8.3.1. Neuromodulation Devices Will be Developed for New Indications: Driving Market Growth
    • 8.3.2. Introduction of Alternative Treatment Options Can Threaten Market Growth

Appendix A

Appendix B

Visiongain report evaluation form

List of Tables

  • Table 2.1: The US Classification of Medical Devices, 2012
  • Table 2.2: The EU Classification System
  • Table 3.1: The Medical Devices Market: Revenues ($bn) by Sector, 2011
  • Table 3.2: Revenues ($bn) & Market Shares (%) of the Top 10 Companies, 2011
  • Table 3.3: J&J Medical Devices: Revenue ($bn) and Market Shares (%) by Brand, 2011
  • Table 3.4: Siemens Healthcare Medical Devices: Revenues ($bn) and Market Shares (%) by Region, 2011
  • Table 3.5: Medtronic: Revenues ($bn) and Market Shares (%) by Sector, 2011
  • Table 3.6: Baxter International Medical Devices: Revenues ($bn) and Market Shares (%) by Segment, 2011
  • Table 3.7: Philips Healthcare Medical Devices: Revenues ($bn) and Market Shares (%) by Segment, 2011
  • Table 3.8: Roche Medical Devices: Revenues ($bn) and Market Shares (%) by Region, 2011
  • Table 3.9: Abbott Laboratories: Revenues($bn) and Market Shares (%) by Sector, 2011
  • Table 3.10: Stryker Corporation: Revenues ($bn) and Market Shares (%) by Sector, 2011
  • Table 3.11: Becton, Dickinson & Co: Revenues ($bn) and Market Shares (%) by Sector, 2011
  • Table 3.12: Global Medical Device Market: Drivers and Restraints, 2012-2022
  • Table 3.13: Global Medical Device Market Breakdown by Region: Revenues ($bn), 2011-2016
  • Table 3.14: Global Medical Device Market Breakdown by Region: Revenues ($bn), 2016-2022
  • Table 3.15: Medical Device Market: Market Shares (%) by Region, 2011-2022
  • Table 4.1: SWOT Chart for the Medical Device Industry, 2012-2022
  • Table 5.1: Cardiology Device Market: Revenues ($bn), 2011-2016
  • Table 5.2: Cardiology Device Market: Revenues ($bn), 2016-2022
  • Table 5.3: DES Market: Revenues ($bn), 2011-2016
  • Table 5.4: DES Market: Revenues ($bn), 2016-2022
  • Table 5.5: DES Market: Drivers and Restraints
  • Table 5.6: Taxus Stents: Revenues ($m) and Market Shares (%) by Region, 2011
  • Table 5.7: Promus Stents: Revenues ($m) and Market Shares (%) by Region, 2011
  • Table 5.8: Coronary Stents Development Pipeline, 2012
  • Table 5.9: SWOT Analysis of the DES market, 2012-2022
  • Table 6.1: Neurological and Neuromodulation Markets: Revenue ($bn) by Sector, 2011
  • Table 6.2: Neurological Device Market: Revenues ($bn), 2011-2016
  • Table 6.3: Neurological Device Market: Drivers & Restraints
  • Table 6.4: Neurological Device Market: Revenues ($bn), 2016-2022
  • Table 6.5: Neuromodulation Device Market: Revenues ($bn), 2011-2016
  • Table 6.6: Neuromodulation Device Market: Revenues ($bn), 2016-2022
  • Table 6.7: SCS Device Market: Revenues ($bn), 2011-2016
  • Table 6.8: SCS Device Market: Revenues ($bn), 2016-2022
  • Table 6.9: DBS Device Market: Revenues ($bn), 2011-2016
  • Table 6.10: DBS Device Market: Revenues ($bn), 2016-2022
  • Table 6.11: VNS Device Market: Revenues ($bn), 2011-2016
  • Table 6.12: VNS Device Market: Revenues ($bn), 2016-2022
  • Table 6.13: Other Neuromodulation Devices: Revenues ($bn), 2011-2016
  • Table 6.14: Other Neuromodulation Devices: Revenues ($bn), 2016-2022
  • Table 6.15: Market Shares (%) of the Leading Segments in the Neuromodulation Devices Market 2011, 2016 & 2022
  • Table 6.16: Neuromodulation Devices Pipeline, 2012
  • Table 6.17: SWOT Chart for the Neuromodulation Device Industry, 2012-2022

List Of Figures

  • Figure 2.1: The Structure of Sirolimus
  • Figure 2.2: The Structure of Everolimus
  • Figure 2.3: The Structure of Zotarolimus
  • Figure 2.4: The Structure of Paclitaxel
  • Figure 3.1: The Medical Device Market: Global Market Shares (%) by Sector, 2011
  • Figure 3.2: J&J Medical Devices: Market Shares (%) by Brand, 2011
  • Figure 3.3: Siemens Healthcare Medical Devices: Market Shares (%) by Region, 2011
  • Figure 3.4: Medtronic: Market Shares (%) by Sector, 2011
  • Figure 3.5: Baxter International Medical Devices: Market Shares (%) by Segment, 2011
  • Figure 3.6: Philips Healthcare Medical Devices: Market Shares (%) by Sector, 2011
  • Figure 3.7: Roche Medical Devices: Market Shares (%) by Region, 2011
  • Figure 3.8: Abbott Laboratories: Market Shares (%) by Sector, 2011
  • Figure 3.9: Stryker Corporation: Market Shares (%) by Sector, 2011
  • Figure 3.10: Becton, Dickinson & Co: Market Shares (%) by Sector, 2011
  • Figure 3.11: Global Medical Device Market: Revenues ($bn), 2011-2016
  • Figure 3.12: Global Medical Device Market: Revenues ($bn), 2016-2022
  • Figure 3.13: Medical Device Market: Revenues ($bn) for the US, Europe and Japan, 2011-2016
  • Figure 3.14: Medical Device Market: Revenues ($bn) for the US, Europe and Japan, 2016-2022
  • Figure 3.15: Medical Device Market: Revenues ($bn) for China and India, 2011-2016
  • Figure 3.16: Medical Device Market: Revenues ($bn) for China and India, 2016-2022
  • Figure 3.17: Medical Device Market: Market Shares (%) by Region, 2011
  • Figure 3.18: Medical Device Market: Market Shares (%) by Region, 2016
  • Figure 3.19: Medical Device Market: Market Shares (%) by Region, 2022
  • Figure 4.1: Proportion of Population Aged 60 or over: World, 1950-2050
  • Figure 5.1: Cardiology Device Market: Revenues ($bn), 2011-2016
  • Figure 5.2: Cardiology Device Market: Revenues ($bn), 2016-2022
  • Figure 5.3: DES Market: Revenues ($bn), 2011-2016
  • Figure 5.4: DES Market: Revenues ($bn), 2016-2022
  • Figure 5.5: Taxus Stents: Market Shares (%) by Region, 2011
  • Figure 5.6: Promus Stents: Market Shares (%) by Region, 2011
  • Figure 6.1: The Neurological and Neuromodulation Markets: Revenues ($bn) by Sector, 2011
  • Figure 6.2: Neurological Device Market: Revenues ($bn), 2011-2016
  • Figure 6.3: Neurological Device Market : Revenues ($bn), 2016-2022
  • Figure 6.4: Neuromodulation Device Market: Revenues ($bn), 2011-2016
  • Figure 6.5: Neuromodulation Device Market: Revenues ($bn), 2016-2022
  • Figure 6.6: SCS Device Market: Revenues ($bn), 2011-2016
  • Figure 6.7: SCS Device Market: Revenues ($bn), 2016-2022
  • Figure 6.8: DBS Device Market: Revenues ($bn), 2011-2016
  • Figure 6.9: DBS Device Market: Revenues ($bn), 2016-2022
  • Figure 6.10: VNS Device Market: Revenues ($bn), 2011-2016
  • Figure 6.11: VNS Device Market: Revenues ($bn), 2016-2022
  • Figure 6.12: Other Neuromodulation Devices: Revenues ($bn) 2011-2022
  • Figure 6.13: Market Shares (%) of Leading Segments in the Neuromodulation Devices Market, 2011
  • Figure 6.14: Market Shares (%) of Leading Segments in the Neuromodulation Devices Market, 2016
  • Figure 6.15: Market Shares (%) of Leading Segments in the Neuromodulation Devices Market, 2022

Companies Listed

  • Abbott Laboratories
  • Advanced Medical Optics Inc
  • Angiotech Pharmaceuticals
  • Apnex Medical Inc
  • Baxter International
  • Becton, Dickinson & Co
  • Bioabsorbable Vascular Solutions Inc
  • Biosensors International
  • Biotronik SE & Co
  • Boston Scientific
  • Bristol Myers Squibb
  • CeloNova BioSciences Inc
  • Center for Devices and Radiological Health (CDRH) [US]
  • Cerbomed
  • Cerebral Rx
  • ClearStream Technologies Group plc
  • Cochlear Ltd.
  • Conor Medsystems Inc
  • Cordis Corporation
  • CVRx Inc
  • Cyberonics Inc.
  • DePuy Inc
  • ElectroCore
  • EnteroMedics Inc
  • Ethicon Endo-Surgery Inc
  • Ethicon Inc
  • Eucomed
  • European Commission (EC)
  • Food & Drug Administration (FDA) [US]
  • GE Healthcare
  • GlaxoSmithKline (GSK)
  • Global Harmonisation Task Force (GHTF)
  • Guidant Corporation
  • ImThera Medical Inc
  • Insightra Medical
  • Intelect Medical Inc
  • International Medical Device Regulators Forum (IMDRF)
  • International Neuromodulation Society
  • IntraPace Inc
  • Johnson & Johnson (J&J)
  • Johnson & Johnson Vision Care
  • JW Medical Systems
  • Kyoto Medical Planning Co Ltd
  • Labcoat Ltd
  • Lupin Pharmaceuticals Inc
  • Medtronic Inc
  • MetaCure Inc
  • MiCell Technologies Inc
  • MIV Therapeutics Inc
  • National Epilepsy Foundation
  • National Institute for Health and Clinical Excellence (NICE) [UK]
  • Neurologix
  • NeuroPace Inc
  • Northstar Neuroscience Inc
  • Novartis
  • OrbusNeich
  • Ortho-Clinical Diagnostics Inc
  • Patient-Centered Outcomes Research Institute (PCORI) [US]
  • Pfizer
  • Philips Healthcare
  • Roche
  • Samsung
  • Sanofi-aventis
  • Siemens Healthcare
  • St Jude Medical
  • St Michael's Hospital, Toronto (Canada)
  • Stryker Corporation
  • Terumo Medical Corporation
  • Teva Pharmaceutical Industries Ltd
  • Third Wave Technologies Inc
  • Transneuronix Inc
  • UCB Inc
  • United Nations (UN)
  • World Health Organisation (WHO)
  • Wyeth Pharmaceuticals
 

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